The Hugoniot data is in accord with the Los Alamos Scientific Laboratory (LASL) shock Hugoniot data and shows a good linearity over 21 GPa. Polymorphic phase transitions were identified by the kinks in the measured T-H-P-H and C-P-H relationships. The onset pressures of the transformations are similar to 75 and similar to 128 GPa, respectively. A thermodynamic calculation suggests that the phase transition at 75 GPa is its disproportionation to massicot (high pressure phase of PbO) and melted silica
while the transition at 128 GPa is from the melting of massicot. (C) 2011 American Institute of Physics. [doi:10.1063/1.3601115]“
“The benefit of biological therapies in rheumatoid arthritis (RA) treatment is well known, but their role in amyloid A (AA) amyloidosis secondary to RA is unclear.
The aim of this study Selleckchem Ilomastat was to clarify the clinical benefit of etanercept in RA patients with AA amyloidosis. We treated 14 RA patients who had serum amyloid A protein (SAA) 1.3 allele, with biopsy-confirmed AA amyloidosis with etanercept and investigated the efficacy of etanercept treatment, focusing on renal function retrospectively. The AA amyloidosis improved and stabilized after 89.1 +/- 27.2 weeks. Proteinuria decreased from 2.24 +/- 0.81 to 0.57 +/- 0.41 g/day (P<0.01) and SAA fell from 250 +/- 129 to 26 +/- 15 mu g/ml (P<0.01), respectively. Diarrhea secondary to gastrointestinal AA Selleck MEK inhibitor amyloidosis selleck was less. Overall, the serum creatinine levels did not benefit with treatment, but in those with a creatinine values <2.0 mg/dl the creatinine level continued to fall (P=0.021).
Serum albumin increased following 96 weeks of etanercept treatment (P=0.003). Etanercept treatment led to clinical improvement in proteinuria and serum albumin levels accompanied by a fall in SAA levels.”
“This study compares the properties of a highly conductive polymer based on polypyrrole and multiwall carbon nanotubes (MWCNTs) grafted with poly (styrenesulfonic acid) (PPy/MWCNT-gr-PSSA) prepared for flexible indium tin oxide-free organic solar cell (OSC) anode with those of PH500 poly(3,4-ethylenedioxythiophene) : poly(styrenesulfonate) (PEDOT : PSS) in various solvents. Hydrophilic poly(styrenesulfonic acid) (PSSA) was grafted on the MWCNT surfaces to improve dispersion of the MWCNT in an aqueous solution. MWCNT-gr-PSSA was added because MWCNT acts as a conductive additive and a template for the polymerization of PPy. Polymerization yields increased as the amount of MWCNT-gr-PSSA increased and reached a maximum when 50% of MWCNT-gr-PSSA was added. The conductivity of PPy/MWCNT-gr-PSSA composite was further improved and the value reached similar to 152 S/cm with the addition of a toluenesulfonic acid (TSA)/HCl dopant mixture.