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h. Cora aff. glabrata (Robert Lücking, Colombia). i. Corella brasiliensis (Robert Lücking, Colombia). j. OICR-9429 cell line Dictyonema sericeum AZD2281 nmr (Robert Lücking 0411, Colombia). k–l. Tribe Cantharelluleae. k. Cantharellula umbonata (Drew Parker, California, USA). l. Pseudoarmillariella ectypoides (Renée LeBeuf, Quebéc, Canada). m–r. Cuphophylloid grade. m–p. Cuphophyllus. m. Section Cuphophyllus, C. pratensis (F.

Boccardo, Italy). n. Section Fornicati, C. fornicatus (Jan Vesterholt, Denmark). o. Section Adonidum, C. adonis (Mathew Smith, Argentina). p. Section Virginei, C. virgineus (Jan Vesterholt, Denmark). q. Cantharocybe brunneovelutina (D. Jean Lodge, Belize). r. Ampulloclitocybe clavipes (Jens H. Petersen/Mycokey, Denmark). Scale bar = 1 cm Phylogenetic support Only our Supermatrix analysis includes more than one species of Ampulloclitocybe (A. clavipes and A. avellaneoalba (Murrill) Harmaja), which shows100 % MLBS support for the Ampulloclitocybe clade, and 65 % support for it being sister to Cantharocybe. Our 4-gene backbone analysis also shows Ampulloclitocybe as sister to Cantharocybe, but with low support (35 % MLBS). Binder et al. (2010) show the same pairing of Ampulloclitocybe and Cantharocybe, also without significant support in their six-gene mTOR inhibitor analysis.

Our ITS-LSU analysis places Ampulloclitocybe as basal to both Cantharocybe and Cuphophyllus, but with low support Fig. (41 % MLBS; Fig. 22). In contrast, our LSU analysis places Cantharocybe near Cuphophyllus but Ampulloclitocybe as sister to Omphalina s.s., but without significant support. Moncalvo et al. (2002) show MPBS support for placing Ampulloclitocybe as basal in the Omphalina clade in their LSU analysis. Species included Type Ampulloclitocybe clavipes (Pers.) Redhead, Lutzoni, Moncalvo & Vilgalys, and A. avellaneoalba. Harmaja Methane monooxygenase (2003) also placed Clitocybe squamulosoides P.D. Orton in Ampulloclitocybe, but this needs to be verified by molecular analyses. Comments As discussed in Redhead et al. (2002), Bigelow’s lectotypification of gen. Clitocybe with Clitocybe clavipes is rejected because of earlier typifications (Greuter et al. 2000, Art. 9.17). Harmaja (2002) also described a new genus, “Clavicybe”

Harmaja, illeg., based on the same type as Ampulloclitocybe (Agaricus clavipes), but publication of Ampulloclitocybe preceded by 2 months the publication of “Clavicybe”, rendering the latter illegitimate. Scanning electron micrographs of spores of the type, A. clavipes, by Pegler and Young (1971) showed they were minutely ornamented. Ampulloclitocybe clavipes is known to produce a coprine-like (antabuse-like) aldehyde dehydrogenase inhibitor (Cochran and Cochran 1978; Yamaura et al. 1986) as well as a tyrosine kinase inhibitor named clavilactone (Cassinelli et al. 2000). Cantharocybe H.E. Bigelow & A.H. Sm., Mycologia 65(2): 486 (1973), emend. Ovrebo, Lodge & Aime, Mycologia 103(5): 1103 (2011). Type species: Cantharocybe gruberi (A.H. Sm.) H.E.