The novel PU material
was characterized by H-1 NMR, Fourier transform infrared (FTIR) spectrometer, gel permeation chromatography (GPC), elemental analysis, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), and dynamic mechanical analysis (DMA). This facile “”click”" reaction provides a useful tool for the development of novel functional polyurethanes for biomedical applications. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 122: 1251-1257, 2011″
“Background: Choline is essential for infant nutrition, and breast milk is a rich source of this nutrient. Common single nucleotide polymorphisms (SNPs) change dietary requirements for choline intake.
Objective: The aim of this study was to determine whether total choline intake and/or SN-38 molecular weight SNPs influence concentrations of choline and its metabolites in human breast milk and plasma.
Design: https://www.selleckchem.com/products/MS-275.html We gave a total of 103 pregnant women supplemental choline or a placebo from 18 wk gestation to 45 d postpartum and genotyped the women for 370 common SNPs. At 45 d postpartum, we measured choline metabolite concentrations in breast milk and plasma and assessed the dietary intake of choline by using a 3-d food record.
Results: On average, lactating
women in our study ate two-thirds of the recommended intake for choline (Adequate Intake = 550 mg choline/d). Dietary choline intake (no supplement) correlated with breast-milk phosphatidylcholine and plasma choline concentrations. A supplement further increased breast-milk https://www.selleckchem.com/products/Staurosporine.html choline, betaine, and phosphocholine concentrations and increased plasma choline and betaine concentrations. We identified 5 SNPs in MTHFR that altered the slope of the intake-metabolite concentration relations, and we identified 2 SNPs in PEMT that shifted these curves upward. Individuals who shared sets of common SNPs were outliers in plots of intake-metabolite concentration
curves; we suggest that these SNPs should be further investigated to determine how they alter choline metabolism.
Conclusion: Total intake of choline and genotype can influence the concentrations of choline and its metabolites in the breast milk and blood of lactating women and thereby affect the amount of choline available to the developing infant. This study was registered at clinicaltrials.gov as NCT00678925. Am J Clin Nutr 2010; 92: 336-46.”
“In this article, an analytical model for current-induced vortex core displacement is developed. By using this model, one can solve the equations of motion analytically to determine the effects of the adiabatic and nonadiabatic spin-torque terms. The final displacement direction of the vortex core due to the two torque terms mirrors their relative strengths. The resulting vortex core displacement direction combined with the amplitude of the displacement is thus a measure for both torque terms. (C) 2011 American Institute of Physics. [doi: 10.1063/1.