In this study the authors determined
the costs associated with EAC+HT in comparison with those for CVR.
Methods. The authors performed a retrospective case-control analysis of 21 children who had undergone CVR and 21 who had undergone EAC+HT. Eligibility criteria included an age less than 1 year and at least 1 year of clinical follow-up data. Financial and clinical records were reviewed for data related to length of hospital stay and transfusion rates as well as costs associated with physician, hospital, and outpatient clinic visits.
Results. The average age of patients who underwent CVR was 6.8 months compared with 3.1 CBL0137 Apoptosis inhibitor months for those who underwent EAC+HT. Patients who underwent EAC+HT most often required the use of 2 helmets (76.5%), infrequently required a third helmet (13.3%), and averaged 1.8 clinic visits in the first 90 days after surgery. Endoscope-assisted craniectomy plus HT was associated with shorter hospital stays (mean 1.10 vs 4.67 days for CVR, p < 0.0001), a decreased rate of blood BI 2536 mw transfusions (9.5% vs 100% for CVR, p < 0.0001), and a decreased operative time (81.1 vs 165.8 minutes for CVR, p < 0.0001). The overall cost of EAC+HT, accounting for hospital charges, professional and helmet fees, and clinic visits, was also lower than that of CVR ($37,255.99 vs $56,990.46, respectively, p < 0.0001).
Conclusions.
Endoscope-assisted craniectomy plus HT is a less costly surgical option for patients than CVR. In addition, EAC+HT was associated with a lower utilization of perioperative resources. Theses findings suggest that EAC+HT for infants with sagittal synostosis may be a cost-effective first-line surgical option.”
“Two cases of palmoplantar lichen planus with various clinical features. Palmoplantar lichen planus is a rare, localized variant of lichen planus. Although several clinical features of palmoplantar lichen planus may be seen, the erythematous scaly form is most common.
We present two cases of palmoplantar lichen planus that show vesicle-like and petechia-like features, which are uncommon variants of palmoplantar lichen planus.”
“Background: There are contrasting reports from different ethnical groups on the role of -1131T>C single nucleotide polymorphisms (SNPs) in the promoter region of the apolipoprotein VX-689 A5 (APOA5) gene on the development of coronary artery disease (CAD). Here we have studied this association in a sample of the Iranian population.
Methods: Seventy-three angiographically confirmed patients with CAD and 55 healthy individuals were entered into this study. The cases and controls were matched for demographic and serum biochemical parameters. Genotyping for the -1131T>C polymorphism of the APOA5 gene was performed using the mismatch polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method.