2: 1. Overall survival was 78% at the time of follow-up, with death related to meningioma in 7% of the total cohort. Local control was 85% overall, 93% for grade 1 disease, 45% for grade 2 disease and 82% for grade 3 disease. Patients with

non-benign disease were more likely to receive >50 Gy (27% of grade 1 lesions vs 65% of grade 2/3 lesions), but despite this local control remained Dinaciclib chemical structure poor, even with the higher dose delivered (local control 60 and 40% for grade 2 lesions treated with 50 and >50 Gy, respectively, and 100 and 75% for grade 3 lesions treated with 50 and >50 Gy, respectively).

Conclusions: Our cohort of patients had an overall local control and survival similar to those documented from other departments. Grade was an important prognostic factor. Patients selleck inhibitor treated with > 50 Gy had worse local control outcomes, probably due to selection bias. Dose escalation may still be appropriate for high-risk disease, and may be more effective with more conformal techniques, such as intensity-modulated radiotherapy. Estall, V. et al. (2009). Clinical Oncology 21, 745-752 (C) 2009 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.”
“Mesh in pelvic reconstructive surgery is being used increasingly in clinical practice. Complications such as mesh erosion and dyspareunia can cause

significant patient morbidity. In cases where vaginal mesh erosions are large or multifocal resulting in inadequate healthy epithelium for repair, this may lead to recurrent mesh erosion or vaginal stenosis.

Nine patients with AZD1080 supplier synthetic mesh erosion who failed to respond to conservative measures were managed surgically with Surgisis.

The median time at which patients presented with mesh erosion was 12 weeks. The size of erosion ranged from 1 to 4 cm in diameter. At follow-up, five patients were cured, three still had evidence of mesh erosion although the overall defects were smaller, and one patient required further surgery.

With

mesh erosion being a troublesome reality following insertion of synthetic mesh repairs, Surgisis may prove to be a useful option in the treatment of large vaginal mesh defects.”
“Aims: Spinal metastatic disease (SMD) is a serious complication of cancer. To our knowledge, only one population-based study of metastatic spinal cord compression (MSCC) has been carried out. The purpose of the present study was to describe population-based incidences of SMD that required local treatment, such as radiotherapy, surgery or vertebroplasty, including patients with or without cord compression, and to characterise the neurological status of these patients.

Materials and methods: During 18 months, all patients with SMD who received local treatment in the South-Eastern Health Region of Norway (population 2.6 million inhabitants) were identified and their medical records were reviewed.