We examined the association of AAC and FJ OA using logistic regression before and after adjusting for age, sex and body mass index (BMI). Furthermore, we examined the independent effect of AAC on FJ OA after including the known cardiovascular risk factors; diabetes, hypertension, hypercholesterolemia, and smoking.
Results: Low ARC (OR 3.84 [2.33-6.34]; NVP-HSP990 P <= 0.0001) and high ARC (9.84 [5.29-18.3]; <= 0.0001) were strongly associated with
FJ OA, compared with the reference group. After adjusting for age, sex, and BMI, the association with FJ OR was attenuated for both low ARC (1.81 [1.01-3.27]; P=0.05) and high ARC (2.63 [0.99-5.23]; P=0.05). BMI and age were independently and significantly associated with FJ OA. The addition of cardiovascular JNJ-26481585 Epigenetics inhibitor risk factors to the model did not substantially change parameter estimates for either AAC tertile.
Conclusions: AACs were associated with FJ OA in this community-based population, when adjusting for epidemiologic factors
associated with spinal degeneration, and cardiovascular risk factors. Potentially modifiable risk factors for facet degeneration unrelated to conventional biomechanical paradigms may exist. This study is limited by cross-sectional design; longitudinal studies are needed. Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International,”
“Amyloidosis is a disease of unknown etiology characterized by the accumulation of an amorphous proteinaceous material in various organs and tissues of the body. Amyloid goiter is an exceedingly rare pathologic condition due to massive amyloid infiltration of the thyroid tissue. Amyloid goiter occurs in association with both primary and secondary systemic amyloidosis, more commonly in the latter. Preoperatively, it simulates a multinodular goiter, and surgical intervention is often necessary to establish a diagnosis and to relieve compressive symptoms of a neck mass. We present the case of an
85-year-old female patient who presented with a rapidly enlarging goiter. Histologic examination confirmed amyloid goiter.”
“Intestinal electrical stimulation (IES) has been introduced as a potential therapy for obesity. However, it is unknown whether the effects of IES on gastrointestinal motility and food CP-456773 chemical structure intake are location-specific. The aim of this study was to assess the effects of “”appendix”" (cecum in dog) electrical stimulation (AES) on gastric tone, gastric emptying, and food intake in dogs.
Twelve healthy dogs were used in three experiments. In experiments 1 and 2, gastric tone and food intake were studied in six dogs implanted with a gastric cannula and one pair of stimulation electrodes in the “”appendix.”" Experiment 3 was performed to study gastric emptying in six dogs with a duodenal cannula and one pair of stimulation electrodes in the “”appendix.”"
(1) AES resulted in proximal gastric distention, with gastric volume increased from 114.9 +/- 10.