Scalp and earlobe references were compared.

Results. -Although amplitude variability itself was not reduced, a reduced coefficient of variation was obtained with the 128-channel method due to higher SEP amplitudes, compared to the conventional one-channel. method, independent of reference.

Conclusion. -These results suggest that at the cost of some additional preparation time, the 128-channel method can measure SEP amplitude more accurately and might therefore be more sensitive to physiological

and pathological changes.

For optimal amplitude estimation, we recommend to increase the number of centroparietal Caspase Inhibitor VI solubility dmso electrodes or, preferably, to perform at least a 64-channel recording. (C) 2007 Elsevier Masson SAS. All rights reserved.”
“Aim of the study. -To determine whether or not chemosensory event-related brain potentials (CSERP) elicited by nociceptive unilateral intranasal (CO2) trigeminal stimulation are lateralized and, selleckchem if they are, whether this hemispheric lateralization is related to the side of the stimulated nostril.

Methods.

-Nine healthy right-handed subjects participated to the study. CSERPs were recorded after left or right monorhinal CO2 stimulation. Latency and baseline-to-peak amplitude of each CSERP component were compared across stimulation conditions (left and right nostril), scalp locations (lower-frontal, frontal, mid-temporal, central, posterior-temporal, parietal) and hemispheres (left

or right), using a three-factor analysis of variance (ANOVA) for repeated measures.

Results. -Intranasal trigeminal CO2 stimulation elicited a large N400-P550 complex. This complex was preceded by an earlier N300 component. Whatever the stimulated nostril, N300, N400 and P550 amplitudes were significantly higher on the right as compared to the left hemisphere, at lower-frontal recording sites. The side of chemosensory stimulation (left or right nostril) did not significantly affect CSERP components.

Conclusions. -This study showed that in healthy right-handed volunteers with normal olfactory ability, intranasal chemosensory trigeminal stimulation may elicit a series of event-related brain potentials, which all display a significant right-hemisphere Epothilone B (EPO906, Patupilone) predominance, irrespective of the stimulated nostril. The observed lateralization was maximal at lower-frontal recording sites. (C) 2008 Elsevier Masson SAS. All rights reserved.”
“The value of various indexes to characterize the stimulus-response curve of human motor nerves was assessed in 40 healthy subjects recruited from four European centers of investigation (Creteil, Lausanne, Liege, Marseille). Stimulus-response curves were established by stimulating the right median and ulnar motor nerves at the wrist, with stimulus durations of 0.